Current Openings


Tarveda Therapeutics, Inc. is discovering and developing a new class of potent and selective miniature drug conjugates (Pentarins®) for the treatment of patients with a wide range of solid tumors. Tarveda’s first drug candidate, PEN-221, is a miniature drug conjugate in clinical evaluation for the treatment of patients with somatostatin receptor 2 (SSTR2) expressing neuroendocrine tumors. PEN-221 comprises a peptide that is highly selective for SSTR2 conjugated to the potent cytotoxic payload, DM1, through a tuned cleavable linker.

Tarveda is also advancing its HSP90 binding drug conjugate platform with lead drug candidate PEN-866, which selectively binds in tumors to the activated form of Heat Shock Protein 90 (HSP90) and releases its SN-38 payload, a potent topoisomerase 1 inhibitor. Tarveda’s strategy includes developing its own proprietary miniature drug conjugates as well as applying its miniature drug conjugate platform to enhance the effectiveness of the targeting moieties and novel payloads of pharmaceutical collaborators.

Position Summary:

The Senior Scientist, Formulation and Analytical Development will work in multi-disciplinary teams in a fast-paced environment to advance discovery, preclinical and clinical programs at Tarveda. The Senior Scientist will be responsible for discovery and pre-clinical formulation development, analytical characterization and stability studies to support internal and outsourced animal studies for pre‐clinical research and early stage clinical program support. Additionally, the Senior Scientist will oversee key pre-clinical formulation development activities, from initial feasibility formulations to clinical prototypes.

Essential Functions:

  • Lead technical projects spanning multiple initiatives in small molecule formulation and analytical activities for discovery projects and CMC support.
  • Technical project leadership and strong lab contributions, management of multiple initiatives in small molecule analysis and formulation development.
  • Contribute to strategy and execution of in-house and outsourced animal trials.
  • Collaborate with peers and effectively work in an energized, fast‐paced, cross‐functional and results-oriented research team environment to deliver the objectives of Tarveda in a timely and cost-efficient manner that meets quality requirements.
  • Lead the formulation development of both internal and external pre-clinical studies for discovery programs.
  • Oversee and execute formulation development activities and train junior personnel
  • Lead discovery analytical testing, methods qualification and stability.
  • Author internal reports, methods and protocols and contribute to regulatory submissions.
  • Interact closely with Biology, Chemistry, Drug Product Formulations and management to provide project updates, workflows and timelines/budgets.

Education and Experience:

  • Ph.D. in chemistry with 5+ years or B.S./M.S. with 8+ years of experience in related field is required.
  • Deep understanding of discovery formulation development concepts, analytical methodologies common to the pharmaceutical industry (e.g. HPLC, MS).
  • Good understanding of formulation development for parenteral products, lyophilization processes and delivery systems development.
  • Established background in formulation and analytical development.
  • Experience with managing and mentoring less experienced scientific staff members.

Required Competencies:

  • Team oriented
  • Effective communicator (written and verbal)
  • Detail oriented
  • Independent/self-motivated
  • Vendor Management
  • Results oriented
  • Multi-tasking
  • Strong sense of urgency

Some travel required, less than 10%

To apply, send resume to: careers@tarvedatx.com

Tarveda Therapeutics, Inc. is a vibrant, entrepreneurial EEO employer committed to a diverse and dynamic workplace.

Tarveda Therapeutics, Inc., 134 Coolidge Ave., Watertown, MA 02472
Website: www.tarvedatx.com

There currently no open positions at Tarveda, but if you would like to connect with us regarding future employment opportunities please email careers@tarveda.com.